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甫寸-dr.libo的博客

甫寸之《胃靠养肠靠清》

 
 
 

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关于我

李博 男,中国中医科学院西苑医院 中医消化内科副主任医师,2006年毕业于北京中医药大学。 2005-2012曾担任丁香园循证医学版版主7年, 2014年获得NSFC国家自然科学基金青年项目资助 2015年入选北京市科技新星计划, 2015年入选中国中医科学院西苑医院育才计划。 2016年入选北京中医药传承“双百工程”唐旭东主任医师学术继承人 2016年1月出版小说体中西医消化内科科普书《胃靠养肠靠清》。

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My CSR-TCM for OWS.  

2007-05-07 00:10:03|  分类: 外语学习 |  标签: |举报 |字号 订阅

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My CSR – TCM for OWS.

This is my Cochrane Systematic review —— Traditional Chinese Medicine for Opioid Withdrawal Syndrome.

This is my work I like.

I was studies Evidence based-medicine(EBM) in China west University.

I was training in the Chinese Cochrane Centre (West China Hospital, Sichuan University) until 30 June 2005.

I was studying in the Chinese Cochrane Centre(Chinese Evidence-Based Medicine Centre/Clinical Epidemiology Regional - Resource and Training Center) of West China Hospital, Sichuan University. I appreciate Wu TX and others for help.

I was visiting for National Institute on Drug Dependence of Peking University Health Science Center (former Beijing Medical University).And I am glad to receive help from Professor Zhao Chengzheng. In this month, I and Professor Zhao discuss about my review(CSR) once a week. I appreciate her and Wangbo for help.

So I have just completed this CSR.

I think that this work is hard and exciting.

 

 

This is my synopsis and abstract of my CSR.

Synopsis

We collected articles on traditional Chinese medicine(TCM)  for opioid withdrawal syndrome, which were published in Chinese, English and Japanese worldwide, and had them strictly assessed. Meta analysis for included articles was conducted. It proved that according to the current evidence, Chinese medicine would be effective for the treatment of opioid withdrawal syndrome.

Abstract

Background

Opioid withdrawal syndrome is a set of complex symptoms which will appeare after a period of opioid use and then withdrawal. In clinic, opioid withdrawal syndrome can be divided into acute withdrawal symptoms and protracted withdrawal symptoms, which usually need medication treatment. Literatures indicated that traditional Chinese medicine was a kind of effective method for opioid withdrawal syndrome. But there needs systematic assessment to approve the effectiveness of Traditional Chinese medicine for the management of opioid withdrawal syndrome.

Objectives

To determine the effectiveness of traditional Chinese medicine for opioid withdrawal syndrome.

Search strategy

Detailed search strategies have been provided for each database searched. These have been based on the search strategy developed for MEDLINE but revised appropriately for each database to take account of differences in controlled vocabulary and syntax rules. We have not had any language restrictions.

We have searched the following databases:

1. Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 1, 2005) which includes the Cochrane Drugs and Alcohol Group Trials Register

2. MEDLINE (January 1966 to December 2005)

3. EMBASE (January 1988 to December 2005)

4. CBM (Chinese Biomedical Database)Chinese Biomedical Disc 1978-2005

5. CMCC(Chinese Medical Current Contents) (1994 to December 2005)

6. CNKI(China National Knowledge Infrastructure).

7. Japana Centra Revuo Medicina(http://www.jamas.gr.jp)1983-2005

Selection criteria

Randomised controlled trials or quasi- randomised controlled trials of traditional Chinese medicine for opioid withdrawal syndrome. Adverse events case reports will also be included.

Data collection & analysis

A standardized checklist was used for data collection. Review Manager (Version 4.2.8) was used to analyze the data collected.

Main results

Five articles which met the inclusion criteria were analyzed with meta-analysis. Three of them were about Shenfutuodu capsule and two about Lingyi capsule. They all aimed directly at acute withdrawal syndrome.  We didn't find articles of high-quality aimed at protracted withdrawal syndrome.The result of this systematic evaluation showed that Shenfutuodu and Lingyi capsule are possibly efficacious in the treatment of acute opioid withdrawal syndrome, for others TCM interventions, we are waiting for high-quality clinical articles.

Reviewers' conclusions

Shenfutuodu capsule and Lingyi capsule may be effective traditional Chinese medicines for drug detoxification according to the evidences presently available. There is a need for well-designed randomized controlled trials to evaluate the role of traditional Chinese medicine for opioid withdrawal syndrome.

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